BMC Biochemistry Tutorials

1. Differential modulation of cellular death and survival pathways by conjugated bile acids

By Differential modulation of cellular death and survival pathways by conjugated bile acids Enrique C Torchia3, 1 , Andrew Stolz2 and Luis B Agellon1 1Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids and Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada read more

2. Characterization of yeast histone H3-specific type B histone acetyltransferases identifies an ADA2-independent Gcn5p activity

By Characterization of yeast histone H3-specific type B histone acetyltransferases identifies an ADA2-independent Gcn5p activity Amy R Sklenar and Mark R Parthun Department of Molecular and Cellular Biochemistry, College of Medicine and Public Health, The Ohio State University, Columbus, OH 43210, USA BMC Biochemistry 2004, 5:11     doi:10.... read more

3. Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the m

By Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the mammalian heart William A Taylor1 , Fred Y Xu1 , Brian J Ma1, 3 , Thomas C Mutter1 , Vernon W Dolinsky1, 4 and Grant M Hatch1, 2 read more

4. The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I

By The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I Adriana Ahumada and Yuk-Ching Tse-Dinh Department of Biochemistry and Molecular Biology, New York Medical College Valhalla, NY USA BMC Biochemistry 2002, 3:13     doi:10.1186/1471-2091-3-13 The electronic version of this article is the c... read more

5. Characterization of the aggregates formed during recombinant protein expression in bacteria

By Background: The first aim of the work was to analyze in detail the complexity of the aggregates formed upon overexpression of recombinant proteins in E. coli. A sucrose step gradient succeeded in separating aggregate subclasses of a GFP-GST fusion protein with specific biochemical and biophysical features, providing a novel approach for studying recombinant protein aggregates. Results: The tota... read more

6. Pattern similarity study of functional sites in protein sequences: lysozymes and cystatins

By Background: Although it is generally agreed that topography is more conserved than sequences, proteins sharing the same fold can have different functions, while there are protein families with low sequence similarity. An alternative method for profile analysis of characteristic conserved positions of the motifs within the 3D structures may be needed for functional annotation of protein sequences.... read more