BMC Neuroscience Tutorials

1. The NMDA antagonist memantine affects training induced motor cortex plasticity - a study using transcranial magnetic stimulation [ISRCTN65784760]

By Background: Training of a repetitive synchronised movement of two limb muscles leads to short-term plastic changes in the primary motor cortex, which can be assessed by transcranial magnetic stimulation (TMS) mapping. We used this paradigm to study the effect of memantine, a NDMA antagonist, on short-term motor cortex plasticity in 20 healthy human subjects, and we were especially interested in p... read more

2. An extrahippocampal projection from the dentate gyrus to the olfactory tubercle

By Background: The dentate gyrus is well known for its mossy fiber projection to the hippocampal field 3 (CA3) and its extensive associational and commissural connections. The dentate gyrus, on the other hand, has only few projections to the CA1 and the subiculum, and none have clearly been shown to extrahippocampal target regions. Results: Using anterograde and retrograde tracer techniques in the... read more

3. Hippocampal lesions facilitate instrumental learning with delayed reinforcement but induce impulsive choice in rats

By Hippocampal lesions facilitate instrumental learning with delayed reinforcement but induce impulsive choice in rats Timothy HC Cheung and Rudolf N Cardinal BMC Neuroscience 2005, 6:36     doi:10.1186/1471-2202-6-36 Published   13 May 2005 Abstract (provisional) <... read more

4. Response of SII cortex to ipsilateral, contralateral and bilateral flutter stimulation in the cat

By Response of SII cortex to ipsilateral, contralateral and bilateral flutter stimulation in the cat Mark Tommerdahl1 , Stephen B Simons1 , Joannellyn S Chiu1 , Vinay Tannan1 , Oleg Favorov1 and Barry Whitsel2 1Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC 27599, ... read more

5. Context-dependent selection of visuomotor maps

By Context-dependent selection of visuomotor maps Emilio Salinas Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston-Salem, NC, 27157-1010, USA BMC Neuroscience 2004, 5:47     doi:10.1186/1471-2202-5-47 The electronic version of this article is the complete one and can be found online at... read more

6. Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum

By Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum Martin Storr , Jutta Thammer , Ralf Dunkel , Volker Schusdziarra and Hans-Dieter Allescher Department of Internal Medicine II, Technical University of Munich, Ismaningerstrasse 22, 81675 Munich, Germany BMC Neuroscience 2002, 3:21    ... read more

7. Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism

By Background: High concentrations of glutamate can accumulate in the brain and may be involved in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease. This form of neurotoxicity involves changes in the regulation of cellular calcium (Ca2+) and generation of free radicals such as peroxynitrite (ONOO-). Estrogen may protect against glutamate-induced cell death by reducing the ... read more

8. Co-release of noradrenaline and dopamine in the cerebral cortex elicited by single train and repeated train stimulation of the locus coeruleus

By Co-release of noradrenaline and dopamine in the cerebral cortex elicited by single train and repeated train stimulation of the locus coeruleus Paola Devoto , Giovanna Flore , Pierluigi Saba , Mauro Fa' and Gian Luigi Gessa BMC Neuroscience 2005, 6:31     doi:10.1186/1471-2202-6-31 Published   2 May 2005read more

9. Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons

By Background: The transcription factor AP-1 positively controls synaptic plasticity at the Drosophila neuromuscular junction. Although in motor neurons, JNK has been shown to activate AP-1, a positive regulator of growth and strength at the larval NMJ, the consequences of JNK activation are poorly studied. In addition, the downstream transcriptional targets of JNK and AP-1 signaling in the Drosop... read more

10. A role for cryptochromes in sleep regulation

By A role for cryptochromes in sleep regulation Jonathan P Wisor1 , Bruce F O'Hara2 , Akira Terao3 , Chris P Selby4 , Thomas S Kilduff3 , Aziz Sancar4 , Dale M Edgar1 and Paul Franken2 1Dept. of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford,... read more

11. Response of SI cortex to ipsilateral, contralateral and bilateral flutter stimulation in the cat

By Response of SI cortex to ipsilateral, contralateral and bilateral flutter stimulation in the cat Mark Tommerdahl1 , Stephen B Simons1 , Joannellyn S Chiu1 , Oleg Favorov1 and Barry Whitsel2 1Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC 27599, USA 2Departmen... read more

12. Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions

By Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions Sebastian Breuer1 , Katrin Pech1 , Armin Buss1 , Christoph Spitzer1 , Juris Ozols4 , Elly M Hol5 , Nicole Heussen2 , Johannes Noth1 , Franz-Werner Schwaiger3 and Andreas B Schmitt1 read more

13. Morphological correlates of injury-induced reorganization in primate somatosensory cortex

By Morphological correlates of injury-induced reorganization in primate somatosensory cortex James D Churchill1 , Jason A Tharp2 , Cara L Wellman2 , Dale R Sengelaub2 and Preston E Garraghty2 1Department of Psychology, Saint Louis University, St. Louis, Missouri 63103, USA 2Department of Psychology... read more

14. Top-down and bottom-up modulation of language related areas – An fMRI Study

By Top-down and bottom-up modulation of language related areas – An fMRI Study Tömme Noesselt1, 3 , Nadim Jon Shah2 and Lutz Jäncke3 1Department for Neurology II, Otto-von-Guericke-University, Magdeburg, Germany 2Research Center Juelich, Germany 3Department for Neuropsychology, U... read more