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Photodynamic treatment of targeted cells Number:7,018,395 from the United States Patent and Trademark Office (PTO) owispatent

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Title: Photodynamic treatment of targeted cells

Abstract: The present invention is drawn to methods for photodynamic therapy (PDT) of a target cell, target tissue or target composition in a mammalian subject, using a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. This targeted substance preferably selectively binds to the target cell, target tissue or target composition. Light at a wavelength or waveband corresponding to that which is absorbed by the targeted substance is then administered. The light intensity is relatively low, but a high total fluence is employed to ensure the activation of the targeted photosensitizing agent or targeted prodrug product.

Patent Number: 7,018,395 Issued on 03/28/2006 to Chen


Inventors: Chen; James (Bellevue, WA)
Assignee: Light Sciences Corporation (Snoqualmie, WA)
Appl. No.: 802284
Filed: March 16, 2004

Current U.S. Class: 607/88; 607/89; 604/21; 424/450
Current Intern'l Class: A61N 5/06.7   (20060101); A61K 9/12.7   (20060101)
Field of Search: 607/88,89,90-92 606/2-16 604/21 424/178.1,181.1,182.1,450


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